Key Research Related to ACF’s Mission

◊ Paoloni, Melissa C., Tandle, Anita, et.al.
Launching a Novel Preclinical Infrastructure: Comparative Oncology Trials Consortium Directed Therapeutic Targeting of TNFa to Cancer Vasculature.
PLoS One 30 March 2009
 

◊ Doggy Genes
Molecular biologists have completely sequenced the first dog genome. Understanding how genetics plays a role in canine diseases could lead to new treatments for diseases shared by humans, such as diabetes, epilepsy and cancer.
Courtesy of the American Institute of Physic's Discoveries and Breakthroughs Inside Science program. July 1, 2006
 

◊ Zemke D, Yamini B, Yuzbasiyan-Gurkan V.
Mutations in the juxtamembrane domain of c-KIT are associated with higher grade mast cell tumors in dogs.
Vet Pathol 2002 Sep;39(5):529-35
 

◊ Cooley DM, Beranek BC, Schlittler DL, Glickman NW, Glickman LT, Waters DJ.
Endogenous gonadal hormone exposure and bone sarcoma risk.
Cancer Epidemiol Biomarkers Prev 2002; 11:1434-40.
 

◊ Mohr S, Leikauf GD, Keith G, Rihn BH.
Microarrays as cancer keys: an array of possibilities.
J Clin Oncol 2002;20(14):3165-75.
 

◊ McSweeney PA, Niederwieser D, Shizuru JA, Sandmaier BM, Molina AJ, Maloney DG, Chauncey TR, Gooley TA, Hegenbart U, Nash RA, Radich J, Wagner JL, Minor S, Appelbaum FR, Bensinger WI, Bryant E, Flowers ME, Georges GE, Grumet FC, Kiem HP, Torok-Storb B, Yu C, Blume KG, Storb RF.
Hematopoietic cell transplantation in older patients with hematologic malignancies: replacing high-dose cytotoxic therapy with graft-versus-tumor effects.
Blood 2001 Jun 1; 97(11):3390-400
 

◊ Golub TR, Slonim DK, Tamayo P, Huard C, Gaasenbeek M, Mesirov JP, Coller H, Loh ML, Downing JR, Caligiuri MA, Bloomfield CD, Lander ES.
Molecular classification of cancer: class discovery and class prediction by gene expression monitoring.
Science 1999;286(5439):531-7.
 

◊ Debouck C, Goodfellow PN.
DNA microarrays in drug discovery and development.
Nat Genet 1999;21(1 Suppl):48-50.
 

◊ Dow SW, Elmslie RE, Willson AP, Roche L, Gorman C, Potter TA.
In vivo tumor transfection with superantigen plus cytokine genes induces tumor regression and prolongs survival in dogs with malignant melanoma.
J Clin Invest 1998 Jun 1;101(11):2406-14
 

◊ Knapp DW, Waters DJ.
Naturally occurring cancer in pet dogs: important models for developing improved cancer therapy for humans.
Mol Med Today 1997; 3: 8-11.
 

◊ Withrow SJ, Powers BE, Straw RC, Wilkins RM.
Comparative aspects of osteosarcoma. Dog versus man.
Clin Orthop 1991; 270: 159-68.