GOAL TWO:
To educate the public and scientific community about the
biologic similarity of cancer in pets and people; also,
to communicate the ways in which comparative oncology is
accelerating the treatment, prevention and ultimate eradication
of cancer.
 In
addition to discovering effective new ways for treating
cancer in pets, ACF expects these advances may also lead
to more effective, less toxic therapies for people. Because
of many factors, including stringent regulatory controls,
the development and approval of new anticancer treatments
for humans is a lengthy process. ACF’s unique mission
provides another mechanism for evaluating new therapies
and expediting their application for people.
New Approaches to Cancer Treatment
Over the past several years ACF has collaborated with The
Rogosin Institute at the New York Weill Cornell Medical
Center in evaluating the effectiveness of one such novel
approach that involves slowing or eliminating tumor growth
through enhanced biological feedback control. Pets unresponsive
to conventional cancer treatment options were treated with
this new approach. Many showed dramatically prolonged survival
(up to at least three years). In some cases, the tumors
disappeared. This treatment is now about to begin human
trials under an FDA Investigational New Drug License.
In another instance, a study of bone sarcoma in Rottweilers
(a collaboration between Purdue University, The Gerald P.
Murphy Cancer Foundation and ACF), has shown direct implications
for children and adolescents with bone cancer. The findings
were subsequently published in the world’s most widely
read journal on cancer prevention: Cancer Epidemiology,
Biomarkers & Prevention. This study, too, is scheduled
for additional investigative research.
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