GOAL ONE:
To fund and develop research focused on the biologic
similarity of cancer in pets
and people that will expedite therapeutic
and preventive benefits for both.
Dogs and cats frequently develop spontaneous cancer and,
despite the obvious differences between people and pets,
we share many of the same environmental and fundamental
genetics that may lead to cancer. Increasingly, comparative
oncology is affirming that only our domestic pets, and not
laboratory animals such as mice and rats, are the true models
for human cancer.
Pet owners who are not scientifically oriented are often
surprised to discover that animals can even get
cancer. So, in addition to the shock of the diagnosis, the
thought that a beloved pet may have to undergo the animal
equivalent of chemotherapy or radiation is overwhelming.
Owners soon discover, however, that such treatments are
humane, and better tolerated by pets than they are in humans.
As in people, of course, response to therapy varies and,
when currently available treatments prove ineffective or
no treatment for the diagnosis exists, a pet may qualify
for a clinical trial that could save or extend its life.
Until recent years, cancer therapies for pets were adapted
from those used in the treatment of human cancer. All this
is changing, however, as more gentle, less toxic therapies
are being evaluated for the treatment of cancer in pets.
As a consequence, therapies, which are initially developed
to benefit pets, may ultimately lead to improvements in
the prevention and treatment of human cancer.
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